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Avapro
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Generic Name: irbesartan ( ir be SAR tan)
Brand Names: Avapro
What is Avapro?
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Avapro is in a group of drugs called angiotensin II receptor antagonists. It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. It works by decreasing the levels of certain chemicals in the body.
Avapro is used to treat high blood pressure. It is sometimes given together with other blood pressure medications.
Avapro is also used to treat kidney problems caused by type 2 (not insulin-dependent) diabetes.
Avapro may also be used for other purposes not listed in this medication guide.
Important information about Avapro
Do not use Avapro without telling your doctor if you are pregnant. Avapro may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. You should not use Avapro if you are allergic to irbesartan. Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of Avapro. Do not use potassium supplements or salt substitutes while you are taking Avapro, unless your doctor has told you to.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.
Keep using this medication even if you feel fine. High blood pressure often has no symptoms.
In rare cases, Avapro can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.
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Why is Accupril prescribed?
Accupril is used in the treatment of high blood pressure. It can be taken alone or in combination with a thiazide type of water pill such as HydroDIURIL. Accupril is in a family of drugs known as "ACE inhibitors." It works by preventing a chemical in your blood called angiotensin I from converting into a more potent form that increases salt and water retention in your body. Accupril also enhances blood flow throughout your blood vessels. Along with other drugs, Accupril is also prescribed in the treatment of congestive heart failure.
Most important fact about Accupril
You must take Accupril regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Accupril; and you must continue taking it even if you are feeling well. Accupril does not cure high blood pressure; it merely keeps it under control.
How should you take Accupril?
You can take Accupril with or without meals.
Alcohol may increase the effect of Accupril, and could cause dizziness or fainting. Avoid alcoholic beverages until you have checked with your doctor.
Take Accupril exactly as prescribed, and see your doctor regularly to make sure the drug is working properly without unwanted side effects. Do not stop taking Accupril without first consulting your doctor.
If you miss a dose...
Take the forgotten dose as soon as you remember. However, if it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never try to "catch up" by doubling the dose.
Storage instructions...
Accupril can be stored at room temperature. Protect from light.
Accupril side effects
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Accupril.
Side effects may include:
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Why should Accupril not be prescribed?
If you are sensitive to or have ever had an allergic reaction to Accupril or similar drugs, such as Capoten and Vasotec, you should not take Accupril. Make sure your doctor is aware of any drug reactions you have experienced.
Special warnings about Accupril
If you develop swelling of the face, lips, tongue, or throat, or of your arms and legs, or have difficulty swallowing or breathing, you should contact your doctor immediately. You may need emergency treatment.
If you develop abdominal pain with or without nausea and vomiting, contact your doctor. ACE inhibitors such as Accupril have been known to cause intestinal swelling.
You may feel light-headed, especially during the first few days of Accupril therapy. If this occurs, notify your doctor. If you actually faint, stop taking Accupril until you have consulted with your doctor.
Vomiting, diarrhea, and heavy perspiration can all deplete your body fluid; and dehydration can cause your blood pressure to drop. If this leads to light-headedness or fainting, you should check with your doctor.
Inform your doctor or dentist that you are taking Accupril before undergoing surgery or anesthesia.
Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor.
If you develop a sore throat, fever, or any other sign of infection, contact your doctor immediately. It could indicate a more serious illness.
If you are taking Accupril, your doctor will do a complete assessment of your kidney function and will watch it closely as long as you are taking Accupril.
If you notice a yellow tinge to your skin and the whites of your eyes, stop taking the drug and notify your doctor immediately. This could be a sign of liver damage.
The safety and effectiveness of Accupril in children have not been established.
Possible food and drug interactions when taking Accupril
If Accupril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Accupril with the following:
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Special information if you are pregnant or breastfeeding
ACE inhibitors such as Accupril have been shown to cause injury and even death to the unborn child when used in pregnancy during the second and third trimesters. If you are pregnant, your doctor should discontinue Accupril as soon as possible. If you plan to become pregnant, make sure your doctor knows you are taking Accupril. Accupril appears in breast milk and could affect a nursing infant. If Accupril is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.
Recommended dosage for Accupril
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The usual starting dose is 10 or 20 milligrams taken once a day. If you have any problems with your kidneys or if you are also taking a diuretic, your starting dose may be lower. For adults over age 65, the usual starting dose is 10 milligrams. Depending on how your blood pressure responds, your doctor may increase your dose up to a total of 80 milligrams a day taken once a day or divided into two doses.
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Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
A severe drop in blood pressure is the primary sign of an Accupril overdose.
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